Archive for the ‘Kinds of Mesothelioma’ Category

Three Types of Mesothelioma Cancer

Wednesday, August 25th, 2010

There are three types of mesothelioma cancer. This is called a pleural effusion, if the lung disease, affects the abdominal peritoneal effusion and pericardial, if effects on the heart. About 75% of cases of pleural mesothelioma and 20% are peritoneal or pericardial effusion. There are also some other rare types of mesothelioma, the remaining 5%. All these statistics are poorly documented. There are many cases that are undiagnosed or unreported in the world:

Pleural mesothelioma:
Among the various types of cancer, mesothelioma occupy only a small percentage. However, among the various types of mesothelioma, pleural mesothelioma makes about three to four cases documented. In the fluid between the chest and the mesothelium lining is constructed.

Peritoneal mesothelioma:
Peritoneal Mesothelioma is a rare disease. Approximately 10-20% of documented cases of peritoneal mesothelioma diagnosed with mesothelioma. Types of mesothelioma affects the stomach of the patient. Abdominal mesothelial cells do not function properly in this sickness. The disease is caused by inhaling asbestos fibers through the mouth.

Pericardial Mesothelioma:
The rarest of mesothelioma, pericardial mesothelioma, mesothelial layer that affects the liver. The main symptoms of pericardial mesothelioma are chest pain, shortness of breath, fever, heart palpitations, fatigue and cough. Like all types of mesothelioma, there is no cure for this species doctors nothing I can do is pain and discomfort symptoms and help patients reduce comfortable and quiet death.

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Mesothelioma Tumor

Thursday, May 27th, 2010

The surgeries have for this tumor are the extrapleural Pneumonectomy and pleurectomy and decortication.

The Extrapleural Pneumonectomy or pleuropneumonectomía begins with an opening of the chest through the posterolateral aspect of the 6th rib, which is resected. Then there is a dissection between the parietal pleura and intrathoracic fascia. It is important not to injure the superior and inferior vena cava, subclavian vessels, intrathoracic vessels and recurrent laryngeal nerves.

The diaphragm is removed if committed or is suspected, including conporción of peritoneal serosa. The pericardium is opened anteromedially phrenic nerve to expose the hilar vessels and subcarinal lymph nodes. Tumor and lung were resected, and using certain techniques and materials (patches) to prevent cardiac herniation.

The mortality of surgery was 15% to 20% and 35% morbilidaddel few years ago. With the advent of new materials, techniques and drugs, mortality has been reduced to 8% and 15% morbidity. The most frequent postoperative complications are bleeding, respiratory failure, pneumonia, pulmonary embolism, and empyema. After surgery the average lifespan is 14 to 25 months with this technique.

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Symptomatic of Lung Mesothelioma

Monday, May 24th, 2010

Stage 2, 3 and 4:

  • Symptomatic treatment including drainage of effusions, chest tube pleurodesis, or thoracoscopic pleurodesis.
  • Palliative surgical resection in selected patients.
  • Palliative radiotherapy.
  • Chemotherapy with a single agent. It has been reported partial response with doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin and ifosfamide.
  • Combination chemotherapy (under clinical evaluation).
  • Clinical trials of multiple modalities.
  • Intracavitary therapy. It is reported that intrapleural or intraperitoneal administration of chemotherapeutic agents (eg.: Cisplatin, mitomycin and cytarabine) produces transient reduction in the size of the tumor mass and temporal control of spills in small clinical studies. Further studies are needed to define the role of intracavitary therapy.
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OTHER THERAPIES FOR LUNG MESOTHELIOMA

Saturday, May 22nd, 2010
  • IMMUNOTHERAPY: put by systemic interferon b; Another method is to administer IL-2 and activation of lymphocytes killers T ¨ ¨ by the same route. Studies have not been obtained yet, so it’s expensive treatment. But the results seem to be somewhat encouraging.
  • Photodynamic Therapy: This therapy is based on the instillation of light turned on in the intrapleural space after photosensitive drug administration. This would result in tissue necrosis by the release of oxygen radicals and other chemicals that are cytotoxic. The complications of this therapy are fistulas and esophageal perforations.
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Chemotherapy for Lung Cancer

Wednesday, May 19th, 2010

The adjuvant chemotherapy should be administered 4-6 weeks after surgery and be continued por4 to 6 cycles. The most commonly used chemotherapeutic agents are doxorubicin (50-90mg/m2) for 4 weeks and mitomycin, who has lung toxicity in 12 mg/m2 for the same amount of time.

Combinations with other drugs increase the effect slightly. However, administering chemotherapy that are not named, has no meaning for the little effect of the same in this pathology.

Studies have shown that administration of chemotherapeutic agents in the pleural space, had better outcome than administered systemically. However, this scheme leaves out the protocol and should be considered better.

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Lung Mesothelioma Information

Monday, May 17th, 2010

Mesothelioma is a very rare type of cancer in which cancer cells invade the mesothelium, the protective cover that covers most of the internal organs.

The mesothelium is composed of two layers of cells: one layer is in contact with the organ, while the second form a bag around. The mesothelium produces a lubricating fluid that allows the two layers to slide over each other allowing the movements of the body covering (eg, lungs). Depending on their position, the mesothelium given a particular name: the one surrounding the lungs is called pleura, which surrounds the heart called pericardium, which surrounds the testicles is called the tunica vaginalis testis and surrounding the uterus is called uterine serous tunic. Most of the abdominal organs are covered by peritoneum

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Treatment of Lung Mesothelioma

Friday, May 14th, 2010


Surgery.

Used three types of surgery in the treatment of mesoepitelioma. Diagnostic surgery to obtain a sample for biopsy is performed by thoracoscopy (*), by laparoscopy or surgery or pleural mediatinoscopia open. Secondly, palliative surgery include partial pleurectomy pleurodesis, thoracoscopy with pleurodesis and more rarely, pleuroperitoneal shunt. The third is curative surgery involving extrapleural pneumonectomy in order to remove most of the tumor. In most centers, surgery is followed by adjuvant therapy. Not all patients are suitable for this procedure, which otherwise has a 6% mortality

Chemotherapy

Although there have been several chemotherapy regimens, none has proven to be curative. The two most useful (to the effect of reducing the tumor mass and improve the symptoms) are cisplatin + pemetrexed + gemcitabine and cistaplatino. In both cases, dexamethasone is recommended to add folic acid supplements and vitamin B12

Radiotherapy

Radiation therapy has been used for many years with disappointing results due to the diffuse nature of the tumor as it may cause radiation pneumonitis. Only one has been found effective when applied locally in the scar area after surgery to avoid the spread of tumor cells remains

Other treatments under investigation include immunotherapy, gene therapy, photodynamic therapy and some anti-angiogenic agents

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MESOTELIOMA PLEURAL

Wednesday, May 12th, 2010


Pleural mesothelioma is the most frequent, its incidence being 9 times higher than the peritoneal mesothelioma. It is more common in men than in women, being the age of onset of symptoms between 50-70 years with a latency period of 20-40 years. In 80% of cases the etiology is exposure to asbestos dust. Other possible causes of mesothelioma are radiation and polio vaccines contaminated with simian virus SV40. The pleural mesothelioma is about 3% of malignant neoplasms of the pleura, and when the diagnosis is made rapidly and its course is invariably fatal, usually during the next two years.

The most common clinical presentation is diffuse chest pain, which occasionally can be pleuritic or radiating to the shoulder accompanied by pleural effusions. Dyspnea, cough, weakness, malaise and fatigue are usually in advanced stages of the disease. In 89% of cases, the abnormal electrocardiogram abnormalities being more frequent sinus tachycardia (42%), ventricular arrhythmias or headphones (17%) and blockage of a branch bundle (30%)

The most common radiographic finding is an irregular opaque at the periphery of the lung, associated with ipsilateral pleural effusion, with evidence of loss of volume, contraction of the hemithorax committed and no shift of the mediastinum to opposite side, despite significant pleural (*) The diagnosis should be suspected when it is pleural thickening surrounding the lung trapping and fixing the mediastinum.

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Lung Mesothelioma

Wednesday, February 17th, 2010

Lung Mesothelioma is a life-threatening medical condition resulting from infection of the mesothelium by asbestos fibers. This is a rare form of cancer that affects the people who had been in constant contact with asbestos, whether at home or workplace. Medical science describes the disease as a rare cancerous tumor affecting mesothelial tissue that surrounds our vital organs as a protective cover. Three different types of lung cancer, pleura, peritoneum and pericardium, have been identified and named after the regions they inhabit.

Mesothelium is a membranous sac located around the vital organs such as the abdomen, lungs and heart. The liner also helps indirectly the functioning of these bodies too. Asbestos particles, after entering and settling in the layers of mesothelium, the cause abnormal cell function resulting in cancerous tumors. In most cases of mesothelioma, cancer occurs only after decades of exposure to asbestos. This prolonged latency period of altering the diagnosis and timely treatment and limits the prospect of complete cure.
(more…)

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Kinds of Mesothelioma

Tuesday, February 2nd, 2010

There are 5 types of mesothelioma, of which only one is benign, among them we find:

Benign Mesothelioma:
The benign form of mesothelioma is commonly develops in the pleura. This is the only form of mesothelioma which healing and recovery is favorable.

Testicular Mesothelioma:
This is the rarest type of malignant mesothelioma, to date, there have been fewer than 100 reported cases. Testicular mesothelioma develops in the tunica vaginalis of the testes.

Peritoneal Mesothelioma:
This is one that develops in the tissue of the abdominal cavity, known as the peritoneal membrane. Approximately 30% of mesotheliomas are present in patients of this type.

Pericardium Mesothelioma:
This type of mesothelioma develops in the heart tissue, known as the pericardium.

Pleural Mesothelioma:
This type of mesothelioma develops in the tissue of the lungs, known as the pleura. It is the most common form of malignant mesothelioma, about 80 percent of cases are pleural in origin.

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