Malignant Peritoneal Mesothelioma

Posted by Clay Hillary | February 4th, 2010 in Peritoneal Mesothelioma | 1 Comment »

Malignant Peritoneal Mesothelioma

Introduction

Peritoneal Mesothelioma is a rare tumor, may be linked to chronic peritoneal irritants. An association with periodic disease is exceptional.

Exegesis

A 60 year old man is suffering from periodic disease for 30 years marked by acute febrile abdominal sensitive to colchicine. From 1988 to 1995, seizures are accompanied by ascites increasingly abundant, last 2 to 4 weeks but remain sensitive to colchicine. In 1995, another push comes to weight loss and food intolerance. They discovered a mass with peritoneal biopsy (laparotomy) allows the diagnosis of malignant peritoneal mesothelioma. The disadvantage is rapidly evolving.

Conclusion

An abundant and recurrent ascites is rarely described in the Fever. Malignant peritoneal mesothelioma is a rare tumor, whose links with exposure to asbestos are less well established than the pleural form. His clinical and paraclinical are misleading. The diagnosis is histological. The prognosis is gloomy, disappointing treatment. The case described here involves an unusual form of abundant and recurrent ascites in a Fever which followed a rare tumor: Malignant peritoneal mesothelioma that chronic peritoneal inflammation in the absence of other etiological factor this patient may be able to help.

Summary

Peritoneal mesothelioma is a rare malignant neoplasm that might be linked to chronic peritoneal inflammation. As well, the association peritoneal mesothelioma, familial Mediterranean fever is uncommon.

Exegesis

We report the case of a 60-year-old man who presented for 30 years with standard periodic Familial Mediterranean Fever Accompanied by Acute abdominal episodes, sensitive to colchicine. Between 1988 and 1995, acute abdominal episodes were Accompanied by more and more profuse recurrent ascitis, partially resolving under colchicine treatment. In 1995, the last episode was severe (with loss of weight and Inability to tolerate feeding) and conducted to the patient’s death due to peritoneal mesothelioma, as confirmed by the biopsy.

Conclusion

Profuse and recurrent ascitis is unusual in standard periodic familial Mediterranean fever. Asbestos exposure at the origin of peritoneal mesothelioma is not well documented. Furthermore, the disease clinical and paraclinical features are misleading, and the diagnosis is based on histology. The prognosis is severe, and treatment is usually disappointing. Our observation clearly “demonstrates the interconnection between an unusual form of profuse and relapsing ascitis that occurred in the course of a periodic disease and peritoneal mesothelioma. The potential role of recurrent peritonitis related to familial Mediterranean fever in the pathogenesis of the tumor is discussed.


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One Response to “Malignant Peritoneal Mesothelioma”

  1. dewong.com says:

    Malignant Peritoneal Mesothelioma « Peritoneal Mesothelioma…

    Introduction

    Peritoneal Mesothelioma is a rare tumor, may be linked to chronic peritoneal irritants. An association with periodic disease is exceptional.

    Exegesis

    A 60 year old man is suffering from periodic disease for 30 years marked by acute febr…

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